Yep. she knows. She actually first asked if he had been married. When I told her yes, he had been, but he was gay, she casually replied that maybe he just didn't know he was at the time. Then she told me that he "was still freakin' hot".
I agree that I don't know how he would have done in some outrageous comedy, but think he did a fantastic job in these movies, especially considering his previous comedic experience in film was rather limited.